Translational medicine aims to improve human health and longevity by determining the relevance to human disease of novel discoveries in the biological sciences.
Translational medicine seeks to coordinate the use of new knowledge in clinical practice and to incorporate clinical observations and questions into scientific hypotehsis in the laboratory. Thus, it is a bidirectional concept, encompassing so-called bench-to-bedside factors, which aim to increase the efficiency by which new therapeutic strategies developed through basic research are tested clinically, and bedside-to-bench factors, which provide feedback about the applications of new treatments and how they can be improved.
Our services include:
- Design and implementation of time and cost effective nonclinical strategies which are fully compliant with ICH guidelines
- A primary objective is to avoid the needless repetition of studies
- An integrated analysis of nonclinical data (pharmacology, DMPK and toxicology) to identify gaps and issues which could impact progression of a drug candidate in the clinic and/or the marketing and post-marketing phases of development
- Based on a gap-analysis of the integrated data package, preparation of a risk management strategy to resolve nonclinical issues
- Deployment and follow-up of cost and time effective risk management strategies